Title

In vitro screening of some Philippine plant extracts as potential inhibitors of dermatophytes

Date of Publication

1990

Document Type

Master's Thesis

Degree Name

Master of Science in Biology

College

College of Science

Department/Unit

Biology

Thesis Adviser

Esperanza Cabrera

Defense Panel Chair

Josefina De Jesus

Defense Panel Member

Milagros L. Relon
Abelardo Geronimo

Abstract/Summary

Aqueous extracts of fifteen common Philippine plants were screened for their antidermatophytic properties. These were Manqifera indica L., Persea americana Mill., Psidium quajava L., Jasminum sambac L., Raphanus sativus, Sandoricum koetjape (Burm.) (f.) Merr., Bixa orellana L., Lycopersicum lycopersicon (L.) Karsten, Impatiens balsamina L., Moringa oleifera Lam., Coleus sp. Averrhoa carambola L., Bidens pilosa L., Cassia alata L. and Datura metel L.At 1:2.6 dilution Bidens pilosa, S. koetjape, C. alata, I. balsamina, P. quajava, and M. indica showed fungicidal activities against the test dermatophytes-Trichophyton rubrum, Microsporum canis and pidermophyton floccosum. P. americana was also fungicidal to M. canis and E. floccosum but only fungistatic against I. rubrum. Also at 1:2.6 dilution, Datura metel, A. carambola and M. oleifera were fungicidal to E. floccosum and M. canis. The extracts of D. metel, A. carambola and M. oleifera also caused a statistically significant reduction in the diameter of the colony in I. rubrum the colony being 1 - 27 percent, 50 percent and 2-27 percent of the control respectively. Coleus sp. and J. sambac were both fungicidal to E. floccosum and M. canis. However, at 0.05 level of confidence the reduction in Colony diameter of I. rubrum caused by J. sambac was not significant. Coleus sp, did not show any inhibitory action on the growth of I. rubrum. Lycopersicon lycopersicum reduced the size of the colony growth to 84 percent of the control in I. rubrum although this was not statistically significant. Lycopersicon lycopersicum was fungicidal to M. canis. Raphanus sativus was fungicidal to I. rubrum and M. canis.Bixa orellana significantly (a = 0.05) reduced the diameter of the E. floccosum colony growth to 67 percent of the control I. rubrum colony diameter was also significantly reduced (a = 0.05) to 25 percent of the control. Bixa orellana did not affect the growth of M. canis.

Abstract Format

html

Format

Print

Accession Number

TG01850

Shelf Location

Archives, The Learning Commons, 12F Henry Sy Sr. Hall

Physical Description

79 p., 28 cm.

Keywords

Plants -- Analysis; Plant extracts -- Analysis

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