Bioactive secondary metabolites from six trees of the family fabaceae (leguminosae)
Date of Publication
2002
Document Type
Dissertation
Degree Name
Doctor of Philosophy in Chemistry
Subject Categories
Chemistry
College
College of Science
Department/Unit
Chemistry
Thesis Adviser
Consolacion Y. Ragasa
Defense Panel Chair
Jaime Raul O. Janairo
Defense Panel Member
Glenn V. Alea
Nancy Lazaro-Llanos
Eric R. Punzalan
Alice Aguinaldo
Abstract/Summary
A total of nineteen compounds are isolated from the six trees covered in this study.Four new cassane diterpenes 6B-hydroxy-vouacapen-5a-01 (CB33), 6B-benzoyl-7B-hydroxy-vouacapen-5a-01 (CB26) and 6B-benzoyl-8,9,11, 14-didehydro-vouacapen-5a-01 (CB 'isomer') were obtained from the DCM extract of Caesalpinia pulcherrima. Their structures were elucidated by extensive ID and 2D NMR analysis. CB22, a probable new furanoditerpene monoacetate variation of CB33, could not be fully elucidated due to its minimal amount and the presence of impurities. Four known compounds were also isolated namely, benzyl 2,6-dimethoxybenzoate (CB8), phytol (CB23), sitosterol (CB25), and squalene (CB36).The ethyl acetate extract of Pithecolobium dulce afforded kaempferol 3-a-L-rhamnoside (KM) and a 2:1 mixture of 1,3-glyceryl diacetate (KM3a) and 1,2-glyceryl diacetate (KM3b). Their structures were elucidated by 1D and 2D NMR analysis.
Abstract Format
html
Language
English
Format
Accession Number
TG03251
Shelf Location
Archives, The Learning Commons, 12F Henry Sy Sr. Hall
Physical Description
412 leaves
Keywords
Plant metabolites; Trees; Legumes; Microbial sensitivity tests; Chemistry, Analytic
Recommended Citation
Hofileña, J. G. (2002). Bioactive secondary metabolites from six trees of the family fabaceae (leguminosae). Retrieved from https://animorepository.dlsu.edu.ph/etd_doctoral/1210
