Isolation and antimutagenicity potential of components from the Ethyl Acetate Extract of Premna odorata

Date of Publication

2001

Document Type

Bachelor's Thesis

Degree Name

Bachelor of Science in Chemistry

Subject Categories

Chemistry

College

College of Science

Department/Unit

Chemistry

Thesis Adviser

Consolacion Y. Ragasa

Defense Panel Chair

Wyona C. Patalinghug

Abstract/Summary

The ethyl acetate extract of Premna odorata afforded three isolates. H-NMR, IR and UV spectra indicated that isolates 1 (A3) and 3 (A7) are most probably mixtures of unsaturated fatty acids, a diterpene, and a triterpene, while isolate 2 (A4) is a mixture of unsaturated fatty acids and a triacylglycerol. Micronucleus tests of all three isolates indicated a 100% reduction in the number of micronucleated polychromatic erythrocytes (MPCE) induced by Mitomycin-C. Thus, all the isolates tested are antimutagens.

Abstract Format

html

Language

English

Format

Print

Accession Number

TU17498

Shelf Location

Archives, The Learning Commons, 12F, Henry Sy Sr. Hall

Physical Description

iv, 47 leaves: illustrations; 29 cm.

Keywords

Ethyl acetoacetate

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