Title

Antibiotic loaded fly ash-derived geopolymer spheres

Date of Publication

2018

Document Type

Bachelor's Thesis

Degree Name

Bachelor of Science in Biology

College

College of Science

Department/Unit

Biology

Thesis Adviser

Jose Isagani B. Janairo

Defense Panel Chair

Mary Jane C. Flores

Abstract/Summary

The quest for reducing greenhouse gas emissions has resulted in the creation of more innovative and energy-efficient technologies. Porous geopolymers, characterized by their three-dimensional structure with fixed but tunable pore sizes, have captured significant research interest due to their prospective industrial applications. Studies were conducted to evaluate the ability of fly ash-derived geopolymer spheres to act as a drug carrier by loading it with amoxicillin. Preliminary cargo diffusion analysis revealed that amoxicillin dissociated from the matrix gradually, insinuating that the drug was able to leach from the spheres. Initial antibacterial activity of the material was also assessed using a modified disk diffusion assay, resulting in the repression of the growth of Escherichia coli. The results presented suggest a promising drug-carrying potential of the geopolymer, which can be used in diverse applications.

Abstract Format

html

Language

English

Format

Electronic

Accession Number

CDTU017626

Shelf Location

Archives, The Learning Commons, 12F, Henry Sy Sr. Hall

Physical Description

1 computer disc ; 4 3/4 in.

Keywords

Amoxicillin; Escherichia coli; Drug carriers (Pharmacy)

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