Isolation and structural elucidation of the chemical constituents of terminalia foetidissima leaves
Date of Publication
Bachelor of Science in Biochemistry
College of Science
Vincent Antonio Ng
Defense Panel Member
Consolacion Y. Ragasa
Jan-Michael C. Cayme
Jaime Raul O. Janairo
Terminalia foetidissima, locally known as talisay gubat, is a native plant in the Philippines and is found to have antioxidant and cytotoxic properties. The leaves were obtained from Mt. Makiling, Laguna, Philippines. It was air dried for two weeks, ground with a blender and soaked in dicholoromethane for three days. The extract was concentrated in vacuum and was subjected to a normal-phased open column chromatography under DCM-acetone fraction with an increasing 10% v/v. The samples were then concentrated in vacuum and re-chromatographed. The purity was monitored using thin layer chromatography. Those with similar profile was combined and was re-chromatographed until TLC pure. Ten TLC pure isolated samples were then subjected to 600 MHz 1d Â¹H nuclear magnetic resonance (NMR). It was determined that the isolated compounds are hydrocarbon, squalene, cyloeucalenol, and a mixture of 3-epicycloeucalenol, stigmaterol, and Î²-sitosterol. This is the first chemical study on the plant.
Archives, The Learning Commons, 12F, Henry Sy Sr. Hall
48 leaves ; illustrations (some color) ; 28 cm.
Medicinal plants--Philippines; Terminalia foetidissima; Talisay gubat
Gumafelix, R. D. (2018). Isolation and structural elucidation of the chemical constituents of terminalia foetidissima leaves. Retrieved from https://animorepository.dlsu.edu.ph/etd_bachelors/2962