Title

The protective effects of L-carnitine and resveratrol against alcohol-induced liver damage in Mus Musculus

Date of Publication

2012

Document Type

Bachelor's Thesis

Degree Name

Bachelor of Science in Biology

College

College of Science

Department/Unit

Biology

Thesis Adviser

Noel F. Alfonso

Abstract/Summary

Alcoholism is a major problem in the society. There are several food supplements that are claimed to protect liver from alcohol damage and disease. In this study, the effects of the food supplements L-carnitine and resveratrol on the livers of alcohol-treated male whit mice (Mus musculus) were examined. The mice were divided into six groups each consisting of five animals as follows: negative control (-), alcohol control (A), L-carnitine control (LC), resveratrol control (R) L-carnitine + alcohol treatment group (LC+A) and the resveratrol + alcohol treatment groups (R+A) and was treated for 10 days. The alcohol control livers (A) showed signs of severe damage in the sinusoids and hepatocytes. The L-carnitine (LC) and resveratrol (R) control groups showed no significant change as compared to the negative control (-). The L-carnitine + alcohol treatment (LC+A) showed no significant damage, as did the resveratrol + alcohol treatments (R+A). The results indicate a potential protective effect of the two food supplements against alcohol-induced liver damage.

Abstract Format

html

Language

English

Format

Electronic

Accession Number

CDTU019025

Shelf Location

Archives, The Learning Commons, 12F, Henry Sy Sr. Hall

Physical Description

1 computer optical disc ; 4 3/4 in.

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