Document Types
Paper Presentation
School Code
N/A
School Name
Caloocan City Science High School
Research Advisor (Last Name, First Name, Middle Initial)
Dizon, Suzzeth U.
Abstract/Executive Summary
Candida albicans and Trichosporon are fungal species that cause candidiasis and trichosporonosis, which are common fungal infections in the Philippines. Due to its growing resistance to antifungal drugs, studies that explore herbal plant alternatives have arisen. The present study was conducted to evaluate the antimycotic activity of Eleusine indica (Paragis) plant crude extract against C. albicans and Trichosporon spp.. E. indica is an invasive plant native to the Philippines that has been proven to possess bioactive compounds such as flavonoids, alkaloids, steroids, essential oils, coumarins, fatty acids, anthraquinone, yield from the inhibitory extraction method, along with factors such as the choice of solvent, phytoche anthrones, triterpenes, and tannins. It was prepared into 25% and 50% concentrations for treatment. After 42 hours of observation, the treatment showed an inhibitory activity against Trichosporon spp. but no inhibitory activity against C. albicans, which could mainly be due to the plant metabolite mical composition, drying and extraction methods, and biofilm formation, which may contribute to these results.
Keywords
antimycotic; Candida albicans; Trichosporon spp.; Eleusine indica; Paragis
Start Date
13-6-2024 8:00 AM
End Date
13-6-2024 10:00 AM
Research Theme (for Paper Presentation and Poster Presentation submissions only)
Food, Nutrition, and Health (FNH)
Initial Consent for Publication
yes
Statement of Originality
yes
Antimycotic potential of Eleusine indica (Paragis) leaf extract against Candida albicans and Trichosporon spp.
Candida albicans and Trichosporon are fungal species that cause candidiasis and trichosporonosis, which are common fungal infections in the Philippines. Due to its growing resistance to antifungal drugs, studies that explore herbal plant alternatives have arisen. The present study was conducted to evaluate the antimycotic activity of Eleusine indica (Paragis) plant crude extract against C. albicans and Trichosporon spp.. E. indica is an invasive plant native to the Philippines that has been proven to possess bioactive compounds such as flavonoids, alkaloids, steroids, essential oils, coumarins, fatty acids, anthraquinone, yield from the inhibitory extraction method, along with factors such as the choice of solvent, phytoche anthrones, triterpenes, and tannins. It was prepared into 25% and 50% concentrations for treatment. After 42 hours of observation, the treatment showed an inhibitory activity against Trichosporon spp. but no inhibitory activity against C. albicans, which could mainly be due to the plant metabolite mical composition, drying and extraction methods, and biofilm formation, which may contribute to these results.
